近二十年我国杀虫剂毒理学研究进展（Ⅱ） ——昆虫对杀虫剂的抗性研究
Advances in insecticide toxicology in China in the last two decades II: Resistance of insects to insecticides
伍一军
点击：1524次 下载：168次
DOI：10.7679/j.issn.2095-1353.2020.103
作者单位：中国科学院动物研究所
中文关键词：杀虫剂；害虫抗药性；毒性；靶标抗性；代谢抗性；穿透抗性
英文关键词：insecticide; insect resistance; toxicity; target resistance; metabolic resistance; penetration resistance
中文摘要：
本文综述了中国昆虫学家、杀虫剂毒理学研究者与植物保护专家及害虫防治工作者最近20年来在昆虫对杀虫剂的抗性研究方面的进展，并就杀虫剂施用后害虫抗药性的发生、交互抗性的形成、杀虫剂增效剂的使用以延缓抗性的发展做了简要介绍，特别对昆虫抗药性的产生机制，包括靶标抗性、代谢抗性和穿透抗性在内的抗性机理，尤其是细胞色素P450酶系、乙酰胆碱酯酶（AChE）、谷胱甘肽巯基转移酶（GST）、电压门控钠离子通道（VGSC）、P-糖蛋白（P-gp）、乙酰胆碱受体（AChR）、表皮生长因子受体（EGFR）和g-氨基丁酸受体（GABAR）等与杀虫剂抗性相关的基因及其表达产物在昆虫抗药性形成中的作用的研究进行了系统性综述。
英文摘要：
Advances in research on the resistance of
insects to insecticides made by entomologists, insecticide toxicologists, plant
protection and pest control experts in China over the past 20 years is
reviewed. Insecticide resistance, including cross-resistance and the delay, or
prevention, of resistance by applying different insecticides with synergistic
effects, is briefly introduced. Studies on the mechanisms of insecticide
resistance in insects, including target resistance, metabolic resistance, and
penetration resistance, especially the role of the genes such as cytochrome
P450s, acetylcholinesterase (AChE), glutathione S-transferase (GST),
voltage-gated sodium channel (VGSC), P-glycoprotein (P-gp), actylcholine
receptor (AChR), epidermal growth factor receptor (EGFR), and γ-aminobutyric acid
receptor (GABAR), and their expression products in the
development of resistance, are systematically reviewed.