The research progress of morphogenregulated cell morphogenesis during Drosophlia wing disc development
Author of the article:LIU Su Ning,WANG Dan,SHEN Jie
Author's Workplace:Department of Entomology,China Agricultural University,Beijing100193,China
Key Words:morphogen, cell morphogenesis, Drosophila, wing disc
Abstract: Drosophila wing disc is a good model system to study the cell morphogenesis. During the development of the larval wing discs, morphogens secrete from high concentration region to low concentration receiving cells to form a dynamic gradient. Morphogen signaling pathways regulate the cell morphogenesis, survival, proliferation, and differentiation. Up to date, three morphogens have been identified in the wing discs, which are Hedgehog (Hh), Decapentaplegic (Dpp), and Wingless (Wg). In this review, we summarize the functions and discuss the molecular mechanisms of these three morphogens in cell morphogenesis.