[Objectives]  To identify pesticides that are effective against Diaphorina citri Kuwayama but that have low environmental toxicity, and provide a theoretical basis for the comprehensive prevention and control of citrus Huanglongbing (HLB). [Methods]  The toxicity and effectiveness of 12 pesticides was evaluated using the indoor membrane method and field bioassays. The effectiveness of low-toxicity pesticides suitable for spraying on foliage and applying to soil was assessed and optimal concentrations determined. [Results]  Of the 12 pesticides tested for indoor virulence, 48% Clothianidin, 45% Chlorpyrifos, 10% Cyantraniliprole and 20% Dinotefuran were the most virulent to adult D. citri with LC₅₀ of 1.42, 1.48, 1.49, 1.60 mg/L, respectively. The results of field leaf spraying tests showed that applying 20% Dinotefuran and 10% Cyantraniliprole was c. 90% effective after 7 days with a comprehensive effect better than that of the other 10 pesticides. The results of soil-drench tests indicated a cumulative reduction rate of 30%. Thiamethoxam was 100% effective after 7 days, significantly higher than the other four pesticides tested. The efficacy of applying 30% Thiamethoxam to soil at concentrations of 100 mg/L and 150 mg/L reached 60% after 30 days, and 100% after 7 days. [Conclusion]  20% Dinotefuran at 150 mg/mLor 10% Cyantranil at 100 mg/mL were the most effective pesticides and dosages sprayed on foliage, whereas 30% Thiamethoxam at 100 mg/mL was the most effective pesticide applied to soil.