Chinese sacbrood virus is a common disease of Apis cerana cerana that can cause colony collapse and huge losses to the domestic honeybee industry. This paper reviews the symptoms, pathogenic factors and current methods for the prevention and control of this disease, and analyzes the feasibility of using Chinese herbal medicine to prevent and treat it. This analysis is based on the biological activity of Chinese herbal medicine and provides new ideas for the application of active ingredients obtained from this traditional body of knowledge for the prevention and control Chinese sacbrood virus. It is important to protect Apis cerana cerana colonies from the Chinese sacbrood virus while at the same time producing safe and pollution-free products.