【目的】 巢础是人工制造的蜜蜂巢房房基，供蜜蜂筑造巢脾的基础。针对市场上的蜜蜂巢础出现结构单一和质量良莠不齐等问题，江西农业大学蜜蜂研究所根据蜜蜂生物学特性，研制了一种蜜蜂仿生巢础（ZL.201420569243.2）。本文旨在对蜜蜂仿生巢础生产可行性进行评价。【方法】 以西方蜜蜂Apis mellifera为试验材料，分析仿生巢础对蜂群群势、蜂蜜产量以及蜂群抗病性的影响。【结果】 工蜂在仿生巢础上造脾效果良好；使用仿生巢础蜂群群势和蜂蜜产量均显著高于使用普通工蜂巢础蜂群，使用仿生巢础蜂群蜂螨寄生数量高于使用普通工蜂巢础蜂群。【结论】 本研发的仿生巢础的生产和繁殖性能较好，可以在养蜂生产中推广应用。

[Objectives]  Comb foundation is artificially manufactured for bees to build their combs on. However, commercial comb foundations have many disadvantages, such as monotonicity in structure and unevenness in quality. To address these problems, the Honeybee Research Institute of Jiangxi Agricultural University developed a bionic comb foundation (Zl.201420569243.2). This study aims to evaluate the feasibility of using this bionic comb foundation in commercial beekeeping. [Methods]  The effects of the bionic comb foundation on colony size, honey production and Varroa destructor resistance, of the honeybee Apis mellifera, were measured. [Results]  Worker bees quickly accepted and built comb on the bionic foundation. Moreover, the bionic comb foundation significantly increased colony size and honey production relative to the commercial worker comb foundation. The number of Varroa mites in the bionic colony was, however, higher than in the control colony. [Conclusion]  The bionic comb foundation increased both colony size and honey production and therefore has the potential to benefit commercial beekeeping.