【目的】  明确阿维菌素亚致死效应对美国白蛾Hyphantria cunea的毒理作用，为合理使用阿维菌素提供理论依据。【方法】 用含阿维菌素亚致死浓度（LC₁₀和LC₃₀）的人工饲料分别饲喂美国白蛾4、5和6龄幼虫，饲喂72 h后，测定4、5和6龄幼虫生长发育和成虫繁殖能力，对照组为含0.1%二甲基亚砜的水溶液。【结果】 与对照相比，LC₃₀处理组的美国白蛾4龄幼虫生长量受到显著抑制（P<0.05），抑制率为22%，5龄和6龄幼虫无显著差异（P>0.05）；LC₁₀的各处理组均没有显著差异（P>0.05）。LC₃₀处理组的4、5和6龄幼虫发育历期均显著延长（P<0.05），分别较对照延长3.4、2.2和1.7d；LC₁₀的各处理组均没有显著差异（P>0.05）。LC₁₀和LC₃₀各处理组的成虫寿命均显著缩短（P<0.05），与对照相比，LC₁₀各处理组的成虫寿命分别缩短1.0、1.5和1.7 d；LC₃₀各处理组的成虫寿命分别缩短2.7、2.3和2.5 d。LC₁₀、LC₃₀各处理组的化蛹率、羽化率、产卵量和卵孵化率均被显著抑制（P<0.05）。LC₃₀各处理组的化蛹率分别仅为对照的48%、56%和36%。LC₃₀各处理组的羽化率分别仅为对照的47%、66%和33%。LC₁₀各处理组的产卵量分别为对照的88%、80%和66%；LC₃₀处理组分别为对照的78%、68%和49%。LC₁₀各处理组的卵孵化率分别为对照的82%、66%和62%；LC₃₀各处理组分别仅为对照的62%、54%和45%。LC₁₀与LC₃₀处理组相比，4龄幼虫处理组的取食量、发育历期、化蛹率和羽化率，5龄幼虫处理组的发育历期和化蛹率，以及6龄幼虫处理组的羽化率和孵化率差异显著，LC₃₀表现出更强的抑制作用。【结论】 亚致死浓度的阿维菌素能够抑制美国白蛾的生长发育和繁殖能力。

[Objectives]  To clarify the toxicological effect of sublethal doses of avermectin on Hyphantria cunea, and thereby provide a theoretical basis for the rational use of this pesticide. [Methods]  The growth and development of 4^th to 6^th instar H. cunea larvae were measured after these had consumed artificial diets containing sublethal concentrations of abamectin (LC₁₀ or LC₃₀) for 72 h. Control groups were fed an aqueous solution containing 0.1% dimethyl sulfoxide. The reproductive ability of adults obtained from these treatment groups was also measured. [Results] The 4th instar LC₃₀ treatment group grew 22% less than the respective control group (P<0.05), whereas there were no significant differences in growth between the 5th and 6th instar LC₃₀ treatment groups and their respective control groups (P>0.05). There was no significant difference in growth between the LC₁₀ treatment groups and their respective control groups (P>0.05). Development of the 4th, 5th and 6th larval instars in the LC₃₀ treatment groups (3.4, 2.2 and 1.7 days, respectively) was significantly prolonged relative to the respective control groups (P<0.05), but there was no significant difference in the duration of development of the LC₁₀ treatment groups (P>0.05) and the respective control groups. Adult longevity in the LC₁₀ and LC₃₀ treatment groups (1-1.7 and 2.3-2.7 days, respectively) was significantly shorter than that of the respective control groups (P<0.05). The pupation rate, emergence rate, fecundity and hatching rate of the LC₁₀ and LC₃₀ treatment groups were also significantly shorter compared to the respective control groups (P<0.05). Pupation and emergence rates, fecundity, and hatching rate in the LC₃₀ treatment group were 36%-56%, 33%-66%, 49%-78% and 45%-62%, respectively, those of the respective control groups. The fecundity and hatching rate of the LC₁₀ treatment groups were 66-88% and 62-82%, respectively, those of the respective control groups. Only the feeding, larvae period, emergence rates and pupation rates of 4th instar larvae, the larvae period and emergence rates of 5th instar larvae, and the emergence rates and egg hatching rate of 6th instar larvae, were significantly less in the LC₁₀ and LC₃₀ treatment groups than in the respective control groups; the differences were greater for the LC₃₀ treatment group than for the LC₁₀ treatment group. [Conclusion] Exposure of H. cunea larvae to sublethal concentrations of abamectin (LC₁₀ and LC₃₀) inhibits both larval growth and development and the reproductive capacity of larvae that survive to adulthood.