化学信息——蛔甙（Ascarosides）研究进展
Review of ascarosides: A class of components of nematode pheromones
白 茹，孟 洁，吴雅静，周 娇，石 娟，赵莉蔺
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DOI：10.7679/j.issn.2095-1353.2023.039
作者单位：北京林业大学林木有害生物防治北京市重点实验室
中文关键词：化学信息；蛔甙；线虫；生物互作
英文关键词：chemical signal; ascarosides; nematoda; biological interaction
中文摘要：
摘 要 生物体通过化学信息感知环境并调控自身行为和发育。一类小分子化合物——蛔甙（Ascarosides）的发现，使化学通讯的研究进入了一个全新的阶段。蛔甙的结构和功能多样，在线虫中广泛存在，能够调节线虫交配、滞育、觅食、聚集和扩散等多种行为。本文重点总结了蛔甙的结构和功能、生物合成与代谢、信息传递的研究进展，为后续开展化学信息调控理论研究、多物种互作研究和新型防治技术研究提供了参考。
英文摘要：
Abstract Organisms utilize chemical signals to perceive their external environmental and regulate their behavior and development. The discovery of ascarosides; a class of small molecular compounds, has been a breakthrough in the study of nematode pheromones. Ascarosides are structurally and functionally diverse and occur widely in nematodes. They regulate a variety of behaviors, including mating, diapause, foraging, aggregation, and dispersal. This paper primarily summarizes the structure, function, biosynthesis, metabolism and signal transmission of ascarosides, thereby providing a reference for future research on chemical signal regulation theory, multi-species interactions, and the development of novel targeted drugs.