伊维菌素对长角血蜱生长发育及生殖的影响
The effect of ivermectin on the development and reproduction of Haemaphysalis longicornis
王 多；高小贺；刘敬泽
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DOI：10.7679/j.issn.2095-1353.2019.090
作者单位：河北省动物生理生化与分子生物学重点实验室，河北师范大学生命科学学院，石家庄 050024；河北省动物生理生化与分子生物学重点实验室，河北师范大学生命科学学院，石家庄 050024；河北省动物生理生化与分子生物学重点实验室，河北师范大学生命科学学院，石家庄 050024
中文关键词：长角血蜱；伊维菌素；生殖；发育；蜱类防治
英文关键词： Haemaphysalis longicornis; ivermectin; development; reproduction; tick control
中文摘要：【目的】 通过分析宿主皮下注射伊维菌素对长角血蜱生长发育及生殖的影响，进而评价伊维菌素对长角血蜱的防治效果。【方法】 以新西兰白兔为宿主，皮下注射不同剂量伊维菌素，观察幼蜱、若蜱及雌蜱的叮咬率、死亡率、吸血期、饱血体重、产卵量和孵化率等生物学参数，分析伊维菌素对长角血蜱生殖和生长发育的影响。【结果】 伊维菌素对长角血蜱各期蜱虫的叮咬率均无显著影响。与对照组相比，伊维菌素可显著增加幼蜱和若蜱死亡率，延长若蜱和雌蜱的吸血期并降低其饱血体重，降低雌蜱产卵量及卵孵化率，抑制卵巢及卵的发育。【结论】 宿主皮下注射伊维菌素能够显著抑制长角血蜱的发育及生殖，可作为防治长角血蜱的候选杀虫剂
英文摘要：[Objectives] To investigate the effectiveness of injected ivermectin for controlling infestation with Haemaphysalis longicornis. [Methods] Different doses of ivermectin were injected subcutaneously into New Zealand white rabbits infected with H. longicornis. Biological parameters including biting rate, mortality, feeding period, engorgement weight, female fecundity, hatchability, and changes in ovarian morphology and eggs, were measured to determine the effect of ivermectin on the reproduction and development of H. longicornis. [Results] Treatment with ivermectin had no significant effect on the biting rate of larvae, nymphs or adult females, but did significantly increase the mortality of larvae and nymphs, significantly prolonged the feeding period, and reduced the engorged weight of both nymphs and female ticks. Ivermectin also significantly reduced the number of eggs laid per female, hatchability, and inhibited ovarian development. [Conclusion] Injection with ivermectin can effectively suppress the development and reproduction of H. longicornis and could be an effective treatment for controlling this parasite.