[Aim]  To clone the sensory neuron membrane protein (SNMP) genes, GmelSNMP1 and GmelSNMP2, in the antennae of the wax moth, Galleria mellonella, and clarify the expression profiles of these genes in different adult tissues, and thereby provide a foundation for further research on their function. [Methods]  Based on adult antennal transcriptome sequencing data and the identification of G. mellonella SNMPs, the cDNA sequence of GmelSNMP1 and GmelSNMP2, including a complete ORF, was cloned using PCR. Phylogenetic and sequence analysis were used to determine the classification and sequence structure of these genes, and fluorescent, quantitative PCR was used to detect their expression in different adult tissues. [Results]  Full-length cDNA sequences of GmelSNMP1 and GmelSNMP2 (GenBank accession no.: PQ824699 and PQ824700) were successfully cloned. The ORF of the GmelSNMP1 gene contains 1 578 nucleotides, encoding 525 amino acids; The ORF of the GmelSNMP2 gene contains 1 566 nucleotides, encoding 521 amino acids. The N-terminus of GmelSNMP1 and GmelSNMP2 proteins are in two transmembrane domains and a large extracellular circular domain within the cell, sharing similar structural characteristics with the vertebrate CD36 protein family. GmelSNMP1 was predominantly expressed in the antennae, and its expression in the antennae of adult females was significantly higher than in males (P=0.002). GmelSNMP2 was expressed in the antennae of both females and males, as well as in non-antennal tissues. [Conclusion]  These results lay a foundation for further exploring the function of large wax moth SNMPs in detecting sex pheromones and other odor molecules.