[Objectives]  To investigate the potential of Chrysoperla sinica to act as a biological control for Spodoptera frugiperda eggs and larvae. [Methods]  Predatory responses of C. sinica to S. frugiperda eggs and larvae were measured at (25±1) ℃ under laboratory conditions. [Results]  Predatory responses of all larval stages of C. sinica were of the Holling Ⅱ type, and all had high reliability. The theoretical daily maximum predation rate, instantaneous attack rate and processing time of third instar C. sinica larvae on S. frugiperda eggs were 192, 1.06 and 0.005 d, respectively, whereas those of 1st instar larvae were 166.7, 0.889 and 0.006 d, respectively. The interaction coefficients of 1st, 2nd and 3rd instar larvae to S. frugiperda eggs were 0.184, 0.260 and 0.224, respectively. The interference effect was significantly smaller in first and second instar larvae, which indicates that C. sinica can effectively control S. frugiperda eggs. [Conclusion]  The results show that C. sinica is a potential biological control agent for the eggs and 1st and 2nd instars of S. frugiperda.