[Objectives]  To improve the optimal content ratio of artificial dietfor adults of Coccinella septempunctata. [Methods]  An artificial diet for adult was optimized by using an orthogonal design. Shrimp, pollen, lard, and honey were selected as the key factors, and their effects on adult weight gain, preoviposition, survival, egg production and incubation were assessed. [Results]  The results showed that an increased shrimp content of 22.53% in the diet could increase weight gain, survival and egg production. Increased pollen content of 3.76% improved both survival and egg production, and shortened preoviposition. A lard content of 4.69% increased survival, and egg production and hatchability. A honey content of 6.89% could promote egg production and hatching rate of adult. The survival rate and hatchability of C. septempunctata fed the optimized diet were higher than that fed the basal diet (P>0.05), and the weight gain and fecundity of female adults were significantly increased (P<0.05), which were 128.15% and 122.15% higher than that fed the basal diet, respectively. The weight gain of female adults fed the optimized diet were higher than that fed the aphids (P>0.05); and the survival rate, fecundity and hatchability of female adults were reduced, which were 94.44%, 63.97% and 88.30% lower than that fed the aphids, respectively. [Conclusion]  Compared with the basic diet, the artificial diet optimized by orthogonal design was suitable for feeding ladybird adults, which increased body weight, shortened preoviposition, and improved survival rate, egg production and hatching rate. Compared with aphid feeding, the survival rate, egg production and hatchability were reduced, the optimized diet needs further improvement.