Abstract  Fruit flies are destructive quarantine pests that harm horticultural crops. Their wide distribution and high fecundity cause large economic losses to the fruit and vegetable industry. Moreover, adult females lay their eggs within host plant tissue where the larvae feed making them difficult to control. Semiochemicals, including those derived from insects, plants, and other sources, due to their high activity and strong specificity, have become the preferred tools for the environmentally- friendly prevention and control of fruit flies. Therefore this review focuses on semiochemicals related to foraging, mating, and oviposition behavior and the application of these in pest control, and then provides guidance and a theoretical basis for the integrated management of Tephritidae fruit flies.