Recent advances in research on the mechanisms through which parasitoid wasps regulate host immunity and development

Author of the article:YE Gong-Yin1** HU Jian2 ZHU Jia-Ying3 FANG Qi1 YAN Zhi-Chao1 WANG Lei4

Author's Workplace：1. State Key Laboratory of Rice Biology, Ministry of Agriculture and Rural Affairs Key Laboratory of Molecular Biology of Crop Pathogens and Insects & Key Laboratory of Biology of Crop Pathogens and Insects of Zhejiang Province, Institute of Insect Sciences, Zhejiang University, Hangzhou 310058, China; 2. State Key Laboratory of Biocontrol, Sun Yat-sen University, Guangzhou 510275, China; 3. Key Laboratory of Forest Disaster Warning and Control of Yunnan Province, Southwest Forestry University, Kunming 650224, China; 4. College of Life Sciences, Anhui Agricultural University, Hefei 230036, China

Key Words： parasitoid wasps; parasitism factors; host pests; immunity; development

Abstract：

 Parasitoid wasps transmit various kinds of bioactive substances, including venom, polydnavirus, virus-like particles, teratocytes, ovarian proteins, and larval secretions, to their hosts. These substances play significant roles in regulating host physiological processes, such as immunity and development, thereby facilitating the development of the parasitoid’s offspring, either inside (endoparasitoid), or outside (ectoparasitoid), the host’s body. This regulation ultimately results in the death of the host. Since many hosts are important agricultural pests, parasitoid wasps are important biological control agents. There has recently been an increase in research on the mechanisms through which parasitoid wasps regulate their hosts’ physiology. In this article, we review the latest progress in research on the range of substances transmitted by parasitoid wasps, and the mechanisms through which wasps regulate the immunity and development of their hosts.