[Objectives]  Using sex pheromone lures to trap tobacco pests is both environmentally friendly and effective. However, antagonistic interactions may occur when the sex pheromones of more than one pest are simultaneously deployed. Understanding these interactions will allow such combinations of sex pheromones to be avoided. [Methods]  Interactions between different combinations of sex pheromones used to trap Spodoptera litura, Helicoverpa armigera, Helicoverpa assulta, and Agrotis ypsilon, were investigated in Taipingba town, Fengdu county, Chongqing. [Results]  A combination of A. ypsilon and H. assulta sex pheromones caught significant more A. ypsilon moths[(2.83±0.95) moths/trap/day] than those caught by the A. ypsilon pheromone alone [(1.17±0.79) moths/trap/day]. This pheromone combination also caught significantly more H. assulta [(3.00±1.46) moths/trap/day] than traps baited with H. assulta sex pheromone alone [(0.83±0.54) moths/trap/day]. Spodoptera litura sex pheromone caught more S. litura moths [(7.83±1.97) moths/trap/day] than all other lures tested. However, combining this pheromone with either the A. ypsilon, H. armigera, or H. assulta, sex pheromones significantly decreased the number of S. litura moths captured to (2.17±1.08), (2.67±1.26) and (4.33±1.89) moths/trap/day, respectively. [Conclusion]  A combination of H. assulta and A. ypsilon sex pheromones had a significant synergistic effect, but combining S. litura sex pheromones with those of other species significantly decreased the number of S. litura captured.